Please help us help you and fill where relevant:
Your LimeSurvey version: [see right hand bottom of your LimeSurvey admin screen]
Own server or LimeSurvey hosting:
Survey theme/template:
==================
(Write here your question/remark)Survey participants are getting this error - Could not open temporary upload directory " on different pages while doing the survey. It has occurred numerous times. Most of the participants can't navigate the survey because of this error. How to deal with it? 

You did not respond the basic questions at the beginning, you don't tell us what version you are using, basically you tell us nothing. How are we supposed to help?

What version of LS are you running?
Where is your installation hosted?
Is the issue just with a specific survey or with other surveys as well?
Does your survey include a file upload question?

Give us something to work with...